Sequential Double “Clicks” toward Structurally Well‐Defined Heterogeneous N‐Glycoclusters: The Importance of Cluster Heterogeneity on Pattern Recognition In Vivo

Structurally well‐defined heterogeneous N‐glycoclusters are prepared on albumin via a double click procedure. The number of glycan molecules present, in addition to the spatial arrangement of glycans in the heterogeneous glycoclusters, plays an important role in the in vivo kinetics and organ‐select...

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Autores principales: Latypova, Liliya, Sibgatullina, Regina, Ogura, Akihiro, Fujiki, Katsumasa, Khabibrakhmanova, Alsu, Tahara, Tsuyoshi, Nozaki, Satoshi, Urano, Sayaka, Tsubokura, Kazuki, Onoe, Hirotaka, Watanabe, Yasuyoshi, Kurbangalieva, Almira, Tanaka, Katsunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323863/
https://www.ncbi.nlm.nih.gov/pubmed/28251056
http://dx.doi.org/10.1002/advs.201600394
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author Latypova, Liliya
Sibgatullina, Regina
Ogura, Akihiro
Fujiki, Katsumasa
Khabibrakhmanova, Alsu
Tahara, Tsuyoshi
Nozaki, Satoshi
Urano, Sayaka
Tsubokura, Kazuki
Onoe, Hirotaka
Watanabe, Yasuyoshi
Kurbangalieva, Almira
Tanaka, Katsunori
author_facet Latypova, Liliya
Sibgatullina, Regina
Ogura, Akihiro
Fujiki, Katsumasa
Khabibrakhmanova, Alsu
Tahara, Tsuyoshi
Nozaki, Satoshi
Urano, Sayaka
Tsubokura, Kazuki
Onoe, Hirotaka
Watanabe, Yasuyoshi
Kurbangalieva, Almira
Tanaka, Katsunori
author_sort Latypova, Liliya
collection PubMed
description Structurally well‐defined heterogeneous N‐glycoclusters are prepared on albumin via a double click procedure. The number of glycan molecules present, in addition to the spatial arrangement of glycans in the heterogeneous glycoclusters, plays an important role in the in vivo kinetics and organ‐selective accumulation through glycan pattern recognition mechanisms. [Image: see text]
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spelling pubmed-53238632017-03-01 Sequential Double “Clicks” toward Structurally Well‐Defined Heterogeneous N‐Glycoclusters: The Importance of Cluster Heterogeneity on Pattern Recognition In Vivo Latypova, Liliya Sibgatullina, Regina Ogura, Akihiro Fujiki, Katsumasa Khabibrakhmanova, Alsu Tahara, Tsuyoshi Nozaki, Satoshi Urano, Sayaka Tsubokura, Kazuki Onoe, Hirotaka Watanabe, Yasuyoshi Kurbangalieva, Almira Tanaka, Katsunori Adv Sci (Weinh) Communications Structurally well‐defined heterogeneous N‐glycoclusters are prepared on albumin via a double click procedure. The number of glycan molecules present, in addition to the spatial arrangement of glycans in the heterogeneous glycoclusters, plays an important role in the in vivo kinetics and organ‐selective accumulation through glycan pattern recognition mechanisms. [Image: see text] John Wiley and Sons Inc. 2016-11-28 /pmc/articles/PMC5323863/ /pubmed/28251056 http://dx.doi.org/10.1002/advs.201600394 Text en © 2016 The Authors. Published by WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Communications
Latypova, Liliya
Sibgatullina, Regina
Ogura, Akihiro
Fujiki, Katsumasa
Khabibrakhmanova, Alsu
Tahara, Tsuyoshi
Nozaki, Satoshi
Urano, Sayaka
Tsubokura, Kazuki
Onoe, Hirotaka
Watanabe, Yasuyoshi
Kurbangalieva, Almira
Tanaka, Katsunori
Sequential Double “Clicks” toward Structurally Well‐Defined Heterogeneous N‐Glycoclusters: The Importance of Cluster Heterogeneity on Pattern Recognition In Vivo
title Sequential Double “Clicks” toward Structurally Well‐Defined Heterogeneous N‐Glycoclusters: The Importance of Cluster Heterogeneity on Pattern Recognition In Vivo
title_full Sequential Double “Clicks” toward Structurally Well‐Defined Heterogeneous N‐Glycoclusters: The Importance of Cluster Heterogeneity on Pattern Recognition In Vivo
title_fullStr Sequential Double “Clicks” toward Structurally Well‐Defined Heterogeneous N‐Glycoclusters: The Importance of Cluster Heterogeneity on Pattern Recognition In Vivo
title_full_unstemmed Sequential Double “Clicks” toward Structurally Well‐Defined Heterogeneous N‐Glycoclusters: The Importance of Cluster Heterogeneity on Pattern Recognition In Vivo
title_short Sequential Double “Clicks” toward Structurally Well‐Defined Heterogeneous N‐Glycoclusters: The Importance of Cluster Heterogeneity on Pattern Recognition In Vivo
title_sort sequential double “clicks” toward structurally well‐defined heterogeneous n‐glycoclusters: the importance of cluster heterogeneity on pattern recognition in vivo
topic Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323863/
https://www.ncbi.nlm.nih.gov/pubmed/28251056
http://dx.doi.org/10.1002/advs.201600394
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