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Pattern Recognition: Sequential Double “Clicks” toward Structurally Well‐Defined Heterogeneous N‐Glycoclusters: The Importance of Cluster Heterogeneity on Pattern Recognition In Vivo (Adv. Sci. 2/2017)

In article number 1600394, Almira Kurbangalieva, Katsunori Tanaka, and co‐workers at the RIKEN Biofunctional Synthetic Chemistry Laboratory develop a way to engineer glycan complexes—heterogeneous clusters of sugar chains attached to proteins or lipids—in a way that allows the molecules to be transp...

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Detalles Bibliográficos
Autores principales: Latypova, Liliya, Sibgatullina, Regina, Ogura, Akihiro, Fujiki, Katsumasa, Khabibrakhmanova, Alsu, Tahara, Tsuyoshi, Nozaki, Satoshi, Urano, Sayaka, Tsubokura, Kazuki, Onoe, Hirotaka, Watanabe, Yasuyoshi, Kurbangalieva, Almira, Tanaka, Katsunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323872/
http://dx.doi.org/10.1002/advs.201770006
Descripción
Sumario:In article number 1600394, Almira Kurbangalieva, Katsunori Tanaka, and co‐workers at the RIKEN Biofunctional Synthetic Chemistry Laboratory develop a way to engineer glycan complexes—heterogeneous clusters of sugar chains attached to proteins or lipids—in a way that allows the molecules to be transported preferentially to specific organs of the body through pattern recognition mechanisms, depending on the sugar chains contained in the cluster. [Image: see text]