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Development of an ex vivo human-porcine respiratory model for preclinical studies

Anatomical models to study aerosol delivery impose huge limitations and extrapolation to humans remains controversial. This study aimed to develop and validate an ex vivo human-like respiratory tract model easy to use and relevant to compare to in vivo human data. A human plastinated head is connect...

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Detalles Bibliográficos
Autores principales:	Perinel, Sophie, Pourchez, Jérémie, Leclerc, Lara, Avet, John, Durand, Marc, Prévôt, Nathalie, Cottier, Michèle, Vergnon, Jean M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324051/ https://www.ncbi.nlm.nih.gov/pubmed/28233793 http://dx.doi.org/10.1038/srep43121

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