Assessing Physicochemical Properties of Drug Molecules via Microsolvation Measurements with Differential Mobility Spectrometry

[Image: see text] The microsolvated state of a molecule, represented by its interactions with only a small number of solvent molecules, can play a key role in determining the observable bulk properties of the molecule. This is especially true in cases where strong local hydrogen bonding exists betwe...

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Detalles Bibliográficos
Autores principales: Liu, Chang, Le Blanc, J. C. Yves, Schneider, Bradley B., Shields, Jefry, Federico, James J., Zhang, Hui, Stroh, Justin G., Kauffman, Gregory W., Kung, Daniel W., Ieritano, Christian, Shepherdson, Evan, Verbuyst, Mitch, Melo, Luke, Hasan, Moaraj, Naser, Dalia, Janiszewski, John S., Hopkins, W. Scott, Campbell, J. Larry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324087/
https://www.ncbi.nlm.nih.gov/pubmed/28280776
http://dx.doi.org/10.1021/acscentsci.6b00297

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