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Integrated Organotypic Slice Cultures and RT-QuIC (OSCAR) Assay: Implications for Translational Discovery in Protein Misfolding Diseases

Protein misfolding is a key pathological event in neurodegenerative diseases like prion diseases, synucleinopathies, and tauopathies that are collectively termed protein misfolding disorders. Prions are a prototypic model to study protein aggregation biology and therapeutic development. Attempts to...

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Detalles Bibliográficos
Autores principales:	Kondru, Naveen, Manne, Sireesha, Greenlee, Justin, West Greenlee, Heather, Anantharam, Vellareddy, Halbur, Patrick, Kanthasamy, Arthi, Kanthasamy, Anumantha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324099/ https://www.ncbi.nlm.nih.gov/pubmed/28233859 http://dx.doi.org/10.1038/srep43155

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