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Hyodeoxycholic acid derivatives as liver X receptor α and G-protein-coupled bile acid receptor agonists
Bile acids are extensively investigated for their potential in the treatment of human disorders. The liver X receptors (LXRs), activated by oxysterols and by a secondary bile acid named hyodeoxycholic acid (HDCA), have been found essential in the regulation of lipid homeostasis in mammals. Unfortuna...
Autores principales: | De Marino, Simona, Carino, Adriana, Masullo, Dario, Finamore, Claudia, Marchianò, Silvia, Cipriani, Sabrina, Di Leva, Francesco Saverio, Catalanotti, Bruno, Novellino, Ettore, Limongelli, Vittorio, Fiorucci, Stefano, Zampella, Angela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324103/ https://www.ncbi.nlm.nih.gov/pubmed/28233865 http://dx.doi.org/10.1038/srep43290 |
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