Evaluating Variant Calling Tools for Non-Matched Next-Generation Sequencing Data

Valid variant calling results are crucial for the use of next-generation sequencing in clinical routine. However, there are numerous variant calling tools that usually differ in algorithms, filtering strategies, recommendations and thus, also in the output. We evaluated eight open-source tools regar...

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Detalles Bibliográficos
Autores principales: Sandmann, Sarah, de Graaf, Aniek O., Karimi, Mohsen, van der Reijden, Bert A., Hellström-Lindberg, Eva, Jansen, Joop H., Dugas, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324109/
https://www.ncbi.nlm.nih.gov/pubmed/28233799
http://dx.doi.org/10.1038/srep43169

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