Transcriptional mechanism of vascular endothelial growth factor-induced expression of protein kinase CβII in chronic lymphocytic leukaemia cells

A key feature of chronic lymphocytic leukaemia (CLL) cells is overexpressed protein kinase CβII (PKCβII), an S/T kinase important in the pathogenesis of this and other B cell malignancies. The mechanisms contributing to enhanced transcription of the gene coding for PKCβII, PRKCB, in CLL cells remain...

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Detalles Bibliográficos
Autores principales: Al-Sanabra, Ola, Duckworth, Andrew D., Glenn, Mark A., Brown, Benjamin R. B., Angelillo, Piera, Lee, Kelvin, Herbert, John, Falciani, Francesco, Kalakonda, Nagesh, Slupsky, Joseph R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324130/
https://www.ncbi.nlm.nih.gov/pubmed/28233872
http://dx.doi.org/10.1038/srep43228

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