Prévalence des dyslipidémies au laboratoire de biochimie du CHU Aristide le Dantec de Dakar, Sénégal

INTRODUCTION: This study aims to evaluate the prevalence of dyslipidemias among patients who underwent assay of a lipid parameter at the Laboratory of Biochemistry of Aristide Le Dantec University Hospital in 2013. METHODS: We conducted a retrospective study of 1356 patients between ages 10-94 years presenting at the laboratory of Biochemistry of CHU Le Dantec from January to December 2013. All patients who had undergone at least one lipid assay whose results were recorded in the laboratory register were enrolled in the study. Total cholesterol, HDL cholesterol, LDL cholesterol and triglycerides were measured using enzymatic methods (Cobas Integra 400 plus biochemistry analyzer - Roche Diagnostics). RESULTS: The prevalence of dyslipidemia in our study population was 39.30%. The prevalence of hypercholesterolemia, hypo-HDL-cholesterolemia, hyper-HDL-cholesterolemia, hypertriglyceridemia, mixed hyperlipidemia was 30,89% ; 7,30% ; 31,19% ; 0,51% ; 7,22% respectively. The subjects aged 40 to 59 years appeared to be more exposed. Moreover, there was a female predominance in hypercholesterolemia (54.17% vs 45.82%) the hypocholesterolemia (54.54% vs45,45%), and mixed hyperlipidemia (51.08% vs 48.97%). Dyslipidemias were strongly correlated to hypertension and obesity. CONCLUSION: The high prevalence of dyslipidemias found in our study highlights the importance of studying the prevalence of cardiovascular risk factors, in particular dyslipidemias, in Senegalese population.