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Novel synthetic analogues of avian β-defensin-12: the role of charge, hydrophobicity, and disulfide bridges in biological functions

BACKGROUND: Avian β-defensins (AvBD) possess broad-spectrum antimicrobial, LPS neutralizing and chemotactic properties. AvBD-12 is a chemoattractant for avian immune cells and mammalian dendritic cells (JAWSII) — a unique feature that is relevant to the applications of AvBDs as chemotherapeutic agen...

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Detalles Bibliográficos
Autores principales:	Yang, Ming, Zhang, Chunye, Zhang, Michael Z., Zhang, Shuping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324278/ https://www.ncbi.nlm.nih.gov/pubmed/28231771 http://dx.doi.org/10.1186/s12866-017-0959-9

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