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Gastrointestinal symptoms and food intolerance 2 years after laparoscopic Roux‐en‐Y gastric bypass for morbid obesity

BACKGROUND: Laparoscopic Roux‐en‐Y gastric bypass (LRYGB) is an effective treatment for morbid obesity, but might aggravate gastrointestinal complaints and food intolerance. The long‐term prevalence of these symptoms has not been well studied. METHODS: In a cross‐sectional study, all patients who un...

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Autores principales: Boerlage, T. C. C., van de Laar, A. W. J. M., Westerlaken, S., Gerdes, V. E. A., Brandjes, D. P. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324533/
https://www.ncbi.nlm.nih.gov/pubmed/27990637
http://dx.doi.org/10.1002/bjs.10419
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author Boerlage, T. C. C.
van de Laar, A. W. J. M.
Westerlaken, S.
Gerdes, V. E. A.
Brandjes, D. P. M.
author_facet Boerlage, T. C. C.
van de Laar, A. W. J. M.
Westerlaken, S.
Gerdes, V. E. A.
Brandjes, D. P. M.
author_sort Boerlage, T. C. C.
collection PubMed
description BACKGROUND: Laparoscopic Roux‐en‐Y gastric bypass (LRYGB) is an effective treatment for morbid obesity, but might aggravate gastrointestinal complaints and food intolerance. The long‐term prevalence of these symptoms has not been well studied. METHODS: In a cross‐sectional study, all patients who underwent primary LRYGB from May to October 2012 were approached 2 years after surgery to complete a general health questionnaire, the Gastrointestinal Symptom Rating Scale (GSRS), and a food intolerance questionnaire. The results were compared with those for a control group of morbidly obese patients. RESULTS: A total of 249 patients were included for analysis, representing a response rate of 93·9 per cent. Mean(s.d.) total weight loss was 30·8(8·7) per cent. The total mean GSRS score was higher in patients who had LRYGB (median 2·19 versus 1·75 in unoperated patients; P < 0·001); the difference in symptoms of indigestion was most notable (P < 0·001). Food intolerance for specific products was reported by 70·7 (95 per cent c.i. 64·8 to 76·0) per cent of the postoperative patients, for a median of 4 foods. There was a positive correlation between food intolerance and score on the GSRS. There was no correlation between either food intolerance or the total mean GSRS score and weight loss, but there was a correlation between weight loss and abdominal pain. CONCLUSION: At 2 years after surgery, patients undergoing LRYGB for morbid obesity have more gastrointestinal complaints than obese controls. Food intolerance is a common side‐effect of LRYGB independent of degree of weight loss or the presence of other abdominal symptoms.
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spelling pubmed-53245332017-03-08 Gastrointestinal symptoms and food intolerance 2 years after laparoscopic Roux‐en‐Y gastric bypass for morbid obesity Boerlage, T. C. C. van de Laar, A. W. J. M. Westerlaken, S. Gerdes, V. E. A. Brandjes, D. P. M. Br J Surg Original Articles BACKGROUND: Laparoscopic Roux‐en‐Y gastric bypass (LRYGB) is an effective treatment for morbid obesity, but might aggravate gastrointestinal complaints and food intolerance. The long‐term prevalence of these symptoms has not been well studied. METHODS: In a cross‐sectional study, all patients who underwent primary LRYGB from May to October 2012 were approached 2 years after surgery to complete a general health questionnaire, the Gastrointestinal Symptom Rating Scale (GSRS), and a food intolerance questionnaire. The results were compared with those for a control group of morbidly obese patients. RESULTS: A total of 249 patients were included for analysis, representing a response rate of 93·9 per cent. Mean(s.d.) total weight loss was 30·8(8·7) per cent. The total mean GSRS score was higher in patients who had LRYGB (median 2·19 versus 1·75 in unoperated patients; P < 0·001); the difference in symptoms of indigestion was most notable (P < 0·001). Food intolerance for specific products was reported by 70·7 (95 per cent c.i. 64·8 to 76·0) per cent of the postoperative patients, for a median of 4 foods. There was a positive correlation between food intolerance and score on the GSRS. There was no correlation between either food intolerance or the total mean GSRS score and weight loss, but there was a correlation between weight loss and abdominal pain. CONCLUSION: At 2 years after surgery, patients undergoing LRYGB for morbid obesity have more gastrointestinal complaints than obese controls. Food intolerance is a common side‐effect of LRYGB independent of degree of weight loss or the presence of other abdominal symptoms. John Wiley & Sons, Ltd 2016-12-19 2017-03 /pmc/articles/PMC5324533/ /pubmed/27990637 http://dx.doi.org/10.1002/bjs.10419 Text en © 2016 The Authors. BJS published by John Wiley & Sons Ltd on behalf of BJS Society Ltd. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Articles
Boerlage, T. C. C.
van de Laar, A. W. J. M.
Westerlaken, S.
Gerdes, V. E. A.
Brandjes, D. P. M.
Gastrointestinal symptoms and food intolerance 2 years after laparoscopic Roux‐en‐Y gastric bypass for morbid obesity
title Gastrointestinal symptoms and food intolerance 2 years after laparoscopic Roux‐en‐Y gastric bypass for morbid obesity
title_full Gastrointestinal symptoms and food intolerance 2 years after laparoscopic Roux‐en‐Y gastric bypass for morbid obesity
title_fullStr Gastrointestinal symptoms and food intolerance 2 years after laparoscopic Roux‐en‐Y gastric bypass for morbid obesity
title_full_unstemmed Gastrointestinal symptoms and food intolerance 2 years after laparoscopic Roux‐en‐Y gastric bypass for morbid obesity
title_short Gastrointestinal symptoms and food intolerance 2 years after laparoscopic Roux‐en‐Y gastric bypass for morbid obesity
title_sort gastrointestinal symptoms and food intolerance 2 years after laparoscopic roux‐en‐y gastric bypass for morbid obesity
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324533/
https://www.ncbi.nlm.nih.gov/pubmed/27990637
http://dx.doi.org/10.1002/bjs.10419
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