Diagnosis of insulin autoimmune syndrome using polyethylene glycol precipitation and gel filtration chromatography with ex vivo insulin exchange

CONTEXT: Insulin‐binding antibodies may produce severe dysglycaemia in insulin‐naïve patients (‘insulin autoimmune syndrome’ (IAS) or Hirata disease), while rendering routine insulin assays unreliable. OBJECTIVE: To assess the performance of clinically used insulin assays and an optimal analytical a...

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Detalles Bibliográficos
Autores principales: Church, David, Cardoso, Luís, Bradbury, Sonia, Clarke, Catriona, Stears, Anna, Dover, Anna, Halsall, David, Semple, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324546/
https://www.ncbi.nlm.nih.gov/pubmed/27588366
http://dx.doi.org/10.1111/cen.13179

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