Cargando…

Cytokine therapy‐mediated neuroprotection in a Friedreich's ataxia mouse model

OBJECTIVES: Friedreich's ataxia is a devastating neurological disease currently lacking any proven treatment. We studied the neuroprotective effects of the cytokines, granulocyte‐colony stimulating factor (G‐CSF) and stem cell factor (SCF) in a humanized murine model of Friedreich's ataxia...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kemp, Kevin C., Cerminara, Nadia, Hares, Kelly, Redondo, Juliana, Cook, Amelia J., Haynes, Harry R., Burton, Bronwen R., Pook, Mark, Apps, Richard, Scolding, Neil J., Wilkins, Alastair
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324580/ https://www.ncbi.nlm.nih.gov/pubmed/28009062 http://dx.doi.org/10.1002/ana.24846

Ejemplares similares

Bone marrow transplantation stimulates neural repair in Friedreich's ataxia mice
por: Kemp, Kevin C., et al.
Publicado: (2018)

Purkinje cell injury, structural plasticity and fusion in patients with Friedreich’s ataxia
por: Kemp, Kevin C., et al.
Publicado: (2016)

Erratum to: ‘Purkinje cell injury, structural plasticity and fusion in patients with Friedreich’s ataxia’
por: Kemp, Kevin C., et al.
Publicado: (2016)

An open-label pilot study of recombinant granulocyte-colony stimulating factor in Friedreich’s ataxia
por: Kemp, Kevin C., et al.
Publicado: (2022)

Mesenchymal Stem Cells Restore Frataxin Expression and Increase Hydrogen Peroxide Scavenging Enzymes in Friedreich Ataxia Fibroblasts
por: Kemp, Kevin, et al.
Publicado: (2011)

Reductions in kinesin expression are associated with nitric oxide-induced axonal damage
por: Redondo, Juliana, et al.
Publicado: (2015)

Purkinje Cell Pathology and Loss in Multiple Sclerosis Cerebellum
por: Redondo, Juliana, et al.
Publicado: (2014)

The Pathology of Friedreich's Ataxia
por: Rainy, Harry
Publicado: (1905)

Epigenetic-based therapies for Friedreich ataxia
por: Sandi, Chiranjeevi, et al.
Publicado: (2014)

Friedreich's Ataxia
por: Anderson, J. Wallace
Publicado: (1893)

Identification of telomere dysfunction in Friedreich ataxia
por: Anjomani Virmouni, Sara, et al.
Publicado: (2015)

Epigenetics in Friedreich's Ataxia: Challenges and Opportunities for Therapy
por: Sandi, Chiranjeevi, et al.
Publicado: (2013)

Reduced neuroprotective potential of the mesenchymal stromal cell secretome with ex vivo expansion, age and progressive multiple sclerosis
por: Sarkar, Pamela, et al.
Publicado: (2018)

Neuroinflammation in Friedreich’s Ataxia
por: Apolloni, Savina, et al.
Publicado: (2022)

Otoneurological Abnormalities in Patients with Friedreich's Ataxia
por: Zeigelboim, Bianca Simone, et al.
Publicado: (2016)

Reduced expression of mitochondrial fumarate hydratase in progressive multiple sclerosis contributes to impaired in vitro mesenchymal stromal cell-mediated neuroprotection
por: Sarkar, Pamela, et al.
Publicado: (2021)

The Pathogenesis of Cardiomyopathy in Friedreich Ataxia
por: Koeppen, Arnulf H., et al.
Publicado: (2015)

Mesenchymal Stem Cell-Derived Factors Restore Function to Human Frataxin-Deficient Cells
por: Kemp, Kevin, et al.
Publicado: (2017)

Stem Cells from Wildtype and Friedreich’s Ataxia Mice Present Similar Neuroprotective Properties in Dorsal Root Ganglia Cells
por: Jones, Jonathan, et al.
Publicado: (2013)

Characterization of the retinal pigment epithelium in Friedreich ataxia
por: Crombie, Duncan E., et al.
Publicado: (2015)

Is Friedreich ataxia an epigenetic disorder?
por: Kumari, Daman, et al.
Publicado: (2012)

Depressive symptoms in Friedreich ataxia
por: Nieto, Antonieta, et al.
Publicado: (2018)

Heart disease in Friedreich’s ataxia
por: Hanson, Emily, et al.
Publicado: (2019)

Drug Repositioning in Friedreich Ataxia
por: Rufini, Alessandra, et al.
Publicado: (2022)

Two Cases of Friedreich’s Ataxia
por: Stephenson, F. H.
Publicado: (1897)

Respiratory Function in Friedreich’s Ataxia
por: Vinante, Elena, et al.
Publicado: (2022)

Predictors of loss of ambulation in Friedreich's ataxia
por: Rummey, Christian, et al.
Publicado: (2020)

Friedreich Ataxia: Multidisciplinary Clinical Care
por: Lynch, David R, et al.
Publicado: (2021)

FXN Promoter Silencing in the Humanized Mouse Model of Friedreich Ataxia
por: Chutake, Yogesh K., et al.
Publicado: (2015)

Friedreich ataxia in a family from Mali, West Africa/Friedreich ataxia in a Malian family
por: Cissé, Cheick A. K., et al.
Publicado: (2021)

MutLα Heterodimers Modify the Molecular Phenotype of Friedreich Ataxia
por: Ezzatizadeh, Vahid, et al.
Publicado: (2014)

'Mitochondrial energy imbalance and lipid peroxidation cause cell death in Friedreich's ataxia'
por: Abeti, R, et al.
Publicado: (2016)

DNA methylation in Friedreich ataxia silences expression of frataxin isoform E
por: Rodden, Layne N., et al.
Publicado: (2022)

Cellular, Molecular and Functional Characterisation of YAC Transgenic Mouse Models of Friedreich Ataxia
por: Anjomani Virmouni, Sara, et al.
Publicado: (2014)

Anaesthesia for a patient with Friedreich's ataxia
por: Ganesan, Ilango
Publicado: (2011)

Hepatic mitochondrial dysfunction in Friedreich Ataxia
por: Stüwe, Sven H, et al.
Publicado: (2011)

The role of oxidative stress in Friedreich's ataxia
por: Lupoli, Federica, et al.
Publicado: (2017)

Two Cases of Friedreich's Ataxia in Adolescents
por: Fergus, John
Publicado: (1917)

Drosophila melanogaster Models of Friedreich's Ataxia
por: Calap-Quintana, P., et al.
Publicado: (2018)

Autonomic function testing in Friedreich’s ataxia
por: Indelicato, Elisabetta, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_g0okupsf76gnts1dki23cpr26s