Lung neuroendocrine tumours: deep sequencing of the four World Health Organization histotypes reveals chromatin‐remodelling genes as major players and a prognostic role for TERT, RB1, MEN1 and KMT2D

Next‐generation sequencing (NGS) was applied to 148 lung neuroendocrine tumours (LNETs) comprising the four World Health Organization classification categories: 53 typical carcinoid (TCs), 35 atypical carcinoid (ACs), 27 large‐cell neuroendocrine carcinomas, and 33 small‐cell lung carcinomas. A disc...

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Detalles Bibliográficos
Autores principales: Simbolo, Michele, Mafficini, Andrea, Sikora, Katarzyna O, Fassan, Matteo, Barbi, Stefano, Corbo, Vincenzo, Mastracci, Luca, Rusev, Borislav, Grillo, Federica, Vicentini, Caterina, Ferrara, Roberto, Pilotto, Sara, Davini, Federico, Pelosi, Giuseppe, Lawlor, Rita T, Chilosi, Marco, Tortora, Giampaolo, Bria, Emilio, Fontanini, Gabriella, Volante, Marco, Scarpa, Aldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2016
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324596/
https://www.ncbi.nlm.nih.gov/pubmed/27873319
http://dx.doi.org/10.1002/path.4853

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