Defining the purity of exosomes required for diagnostic profiling of small RNA suitable for biomarker discovery

Small non-coding RNAs (ncRNA), including microRNAs (miRNA), enclosed in exosomes are being utilised for biomarker discovery in disease. Two common exosome isolation methods involve differential ultracentrifugation or differential ultracentrifugation coupled with Optiprep gradient fractionation. Gene...

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Detalles Bibliográficos
Autores principales: Quek, Camelia, Bellingham, Shayne A., Jung, Chol-Hee, Scicluna, Benjamin J., Shambrook, Mitch C., Sharples, Robyn A., Cheng, Lesley, Hill, Andrew F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324750/
https://www.ncbi.nlm.nih.gov/pubmed/28005467
http://dx.doi.org/10.1080/15476286.2016.1270005

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