Oral Transmission of L-Type Bovine Spongiform Encephalopathy Agent among Cattle

To determine oral transmissibility of the L-type bovine spongiform encephalopathy (BSE) prion, we orally inoculated 16 calves with brain homogenates of the agent. Only 1 animal, given a high dose, showed signs and died at 88 months. These results suggest low risk for oral transmission of the L-BSE a...

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Detalles Bibliográficos
Autores principales: Okada, Hiroyuki, Iwamaru, Yoshifumi, Imamura, Morikazu, Miyazawa, Kohtaro, Matsuura, Yuichi, Masujin, Kentaro, Murayama, Yuichi, Yokoyama, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2017
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324790/
https://www.ncbi.nlm.nih.gov/pubmed/28098532
http://dx.doi.org/10.3201/eid2302.161416
Descripción
Sumario:To determine oral transmissibility of the L-type bovine spongiform encephalopathy (BSE) prion, we orally inoculated 16 calves with brain homogenates of the agent. Only 1 animal, given a high dose, showed signs and died at 88 months. These results suggest low risk for oral transmission of the L-BSE agent among cattle.

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