Oral Transmission of L-Type Bovine Spongiform Encephalopathy Agent among Cattle

To determine oral transmissibility of the L-type bovine spongiform encephalopathy (BSE) prion, we orally inoculated 16 calves with brain homogenates of the agent. Only 1 animal, given a high dose, showed signs and died at 88 months. These results suggest low risk for oral transmission of the L-BSE a...

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Autores principales: Okada, Hiroyuki, Iwamaru, Yoshifumi, Imamura, Morikazu, Miyazawa, Kohtaro, Matsuura, Yuichi, Masujin, Kentaro, Murayama, Yuichi, Yokoyama, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2017
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324790/
https://www.ncbi.nlm.nih.gov/pubmed/28098532
http://dx.doi.org/10.3201/eid2302.161416
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author Okada, Hiroyuki
Iwamaru, Yoshifumi
Imamura, Morikazu
Miyazawa, Kohtaro
Matsuura, Yuichi
Masujin, Kentaro
Murayama, Yuichi
Yokoyama, Takashi
author_facet Okada, Hiroyuki
Iwamaru, Yoshifumi
Imamura, Morikazu
Miyazawa, Kohtaro
Matsuura, Yuichi
Masujin, Kentaro
Murayama, Yuichi
Yokoyama, Takashi
author_sort Okada, Hiroyuki
collection PubMed
description To determine oral transmissibility of the L-type bovine spongiform encephalopathy (BSE) prion, we orally inoculated 16 calves with brain homogenates of the agent. Only 1 animal, given a high dose, showed signs and died at 88 months. These results suggest low risk for oral transmission of the L-BSE agent among cattle.
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spelling pubmed-53247902017-02-24 Oral Transmission of L-Type Bovine Spongiform Encephalopathy Agent among Cattle Okada, Hiroyuki Iwamaru, Yoshifumi Imamura, Morikazu Miyazawa, Kohtaro Matsuura, Yuichi Masujin, Kentaro Murayama, Yuichi Yokoyama, Takashi Emerg Infect Dis Dispatch To determine oral transmissibility of the L-type bovine spongiform encephalopathy (BSE) prion, we orally inoculated 16 calves with brain homogenates of the agent. Only 1 animal, given a high dose, showed signs and died at 88 months. These results suggest low risk for oral transmission of the L-BSE agent among cattle. Centers for Disease Control and Prevention 2017-02 /pmc/articles/PMC5324790/ /pubmed/28098532 http://dx.doi.org/10.3201/eid2302.161416 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Okada, Hiroyuki
Iwamaru, Yoshifumi
Imamura, Morikazu
Miyazawa, Kohtaro
Matsuura, Yuichi
Masujin, Kentaro
Murayama, Yuichi
Yokoyama, Takashi
Oral Transmission of L-Type Bovine Spongiform Encephalopathy Agent among Cattle
title Oral Transmission of L-Type Bovine Spongiform Encephalopathy Agent among Cattle
title_full Oral Transmission of L-Type Bovine Spongiform Encephalopathy Agent among Cattle
title_fullStr Oral Transmission of L-Type Bovine Spongiform Encephalopathy Agent among Cattle
title_full_unstemmed Oral Transmission of L-Type Bovine Spongiform Encephalopathy Agent among Cattle
title_short Oral Transmission of L-Type Bovine Spongiform Encephalopathy Agent among Cattle
title_sort oral transmission of l-type bovine spongiform encephalopathy agent among cattle
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324790/
https://www.ncbi.nlm.nih.gov/pubmed/28098532
http://dx.doi.org/10.3201/eid2302.161416
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