Determination of Elizabethkingia Diversity by MALDI-TOF Mass Spectrometry and Whole-Genome Sequencing

In a hospital-acquired infection with multidrug-resistant Elizabethkingia, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and 16S rRNA gene analysis identified the pathogen as Elizabethkingia miricola. Whole-genome sequencing, genus-level core genome analysis, and in si...

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Autores principales: Eriksen, Helle Brander, Gumpert, Heidi, Faurholt, Cecilie Haase, Westh, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2017
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324808/
https://www.ncbi.nlm.nih.gov/pubmed/28098550
http://dx.doi.org/10.3201/eid2302.161321
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author Eriksen, Helle Brander
Gumpert, Heidi
Faurholt, Cecilie Haase
Westh, Henrik
author_facet Eriksen, Helle Brander
Gumpert, Heidi
Faurholt, Cecilie Haase
Westh, Henrik
author_sort Eriksen, Helle Brander
collection PubMed
description In a hospital-acquired infection with multidrug-resistant Elizabethkingia, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and 16S rRNA gene analysis identified the pathogen as Elizabethkingia miricola. Whole-genome sequencing, genus-level core genome analysis, and in silico DNA-DNA hybridization of 35 Elizabethkingia strains indicated that the species taxonomy should be further explored.
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spelling pubmed-53248082017-02-24 Determination of Elizabethkingia Diversity by MALDI-TOF Mass Spectrometry and Whole-Genome Sequencing Eriksen, Helle Brander Gumpert, Heidi Faurholt, Cecilie Haase Westh, Henrik Emerg Infect Dis Dispatch In a hospital-acquired infection with multidrug-resistant Elizabethkingia, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and 16S rRNA gene analysis identified the pathogen as Elizabethkingia miricola. Whole-genome sequencing, genus-level core genome analysis, and in silico DNA-DNA hybridization of 35 Elizabethkingia strains indicated that the species taxonomy should be further explored. Centers for Disease Control and Prevention 2017-02 /pmc/articles/PMC5324808/ /pubmed/28098550 http://dx.doi.org/10.3201/eid2302.161321 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Eriksen, Helle Brander
Gumpert, Heidi
Faurholt, Cecilie Haase
Westh, Henrik
Determination of Elizabethkingia Diversity by MALDI-TOF Mass Spectrometry and Whole-Genome Sequencing
title Determination of Elizabethkingia Diversity by MALDI-TOF Mass Spectrometry and Whole-Genome Sequencing
title_full Determination of Elizabethkingia Diversity by MALDI-TOF Mass Spectrometry and Whole-Genome Sequencing
title_fullStr Determination of Elizabethkingia Diversity by MALDI-TOF Mass Spectrometry and Whole-Genome Sequencing
title_full_unstemmed Determination of Elizabethkingia Diversity by MALDI-TOF Mass Spectrometry and Whole-Genome Sequencing
title_short Determination of Elizabethkingia Diversity by MALDI-TOF Mass Spectrometry and Whole-Genome Sequencing
title_sort determination of elizabethkingia diversity by maldi-tof mass spectrometry and whole-genome sequencing
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324808/
https://www.ncbi.nlm.nih.gov/pubmed/28098550
http://dx.doi.org/10.3201/eid2302.161321
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