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Matrix metalloproteinases are possible targets in monocrotaline-induced pulmonary hypertension: investigation of anti-remodeling effects of alagebrium and everolimus

OBJECTIVE: In our study, sildenafil alone and everolimus or alagebrium in combination with sildenafil were investigated in terms of their additional therapeutic and anti-remodeling activity in monocrotaline-induced pulmonary hypertension (PH) model in rats. In particular, the inter-relationships bet...

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Detalles Bibliográficos
Autores principales: Atlı, Özlem, Ilgın, Sinem, Ergun, Bülent, Burukoğlu, Dilek, Musmul, Ahmet, Sırmagül, Başar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kare Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324875/
https://www.ncbi.nlm.nih.gov/pubmed/27182612
http://dx.doi.org/10.14744/AnatolJCardiol.2016.6891