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Cutaneous leukemic infiltration following varicella - a case of Wolf's isotopic response
Wolf's isotopic response designates the appearance of two subsequent unrelated dermatoses in the same anatomic location. We report the case of a 51-year-old man with a medical history of chronic lymphocytic leukemia without known extra-hematopoietic involvement. The patient developed a dissemin...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Dermatologia
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324999/ https://www.ncbi.nlm.nih.gov/pubmed/28300900 http://dx.doi.org/10.1590/abd1806-4841.20164686 |
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author | Brasileiro, Ana Lencastre, André João, Alexandre Fidalgo, Ana |
author_facet | Brasileiro, Ana Lencastre, André João, Alexandre Fidalgo, Ana |
author_sort | Brasileiro, Ana |
collection | PubMed |
description | Wolf's isotopic response designates the appearance of two subsequent unrelated dermatoses in the same anatomic location. We report the case of a 51-year-old man with a medical history of chronic lymphocytic leukemia without known extra-hematopoietic involvement. The patient developed a disseminated papulo-vesiculous eruption, diagnosed as varicella. Few days after recovering, an erythematous and violaceous papular dermatosis with histopathological examination compatible with leukemic infiltration appeared on the scars of previous herpetic lesions. Complete remission was obtained under systemic corticotherapy, without cutaneous recurrence or blastic transformation. Wolf's isotopic response is attributed to a localized immunologic imbalance following a certain stimulus. In this patient, herpetic infection acted as a local spur for inaugural cutaneous leukemic infiltration, with no impact on the prognosis for the underlying disease. |
format | Online Article Text |
id | pubmed-5324999 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Sociedade Brasileira de Dermatologia |
record_format | MEDLINE/PubMed |
spelling | pubmed-53249992017-03-02 Cutaneous leukemic infiltration following varicella - a case of Wolf's isotopic response Brasileiro, Ana Lencastre, André João, Alexandre Fidalgo, Ana An Bras Dermatol Case Report Wolf's isotopic response designates the appearance of two subsequent unrelated dermatoses in the same anatomic location. We report the case of a 51-year-old man with a medical history of chronic lymphocytic leukemia without known extra-hematopoietic involvement. The patient developed a disseminated papulo-vesiculous eruption, diagnosed as varicella. Few days after recovering, an erythematous and violaceous papular dermatosis with histopathological examination compatible with leukemic infiltration appeared on the scars of previous herpetic lesions. Complete remission was obtained under systemic corticotherapy, without cutaneous recurrence or blastic transformation. Wolf's isotopic response is attributed to a localized immunologic imbalance following a certain stimulus. In this patient, herpetic infection acted as a local spur for inaugural cutaneous leukemic infiltration, with no impact on the prognosis for the underlying disease. Sociedade Brasileira de Dermatologia 2016 /pmc/articles/PMC5324999/ /pubmed/28300900 http://dx.doi.org/10.1590/abd1806-4841.20164686 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Brasileiro, Ana Lencastre, André João, Alexandre Fidalgo, Ana Cutaneous leukemic infiltration following varicella - a case of Wolf's isotopic response |
title | Cutaneous leukemic infiltration following varicella - a case of
Wolf's isotopic response |
title_full | Cutaneous leukemic infiltration following varicella - a case of
Wolf's isotopic response |
title_fullStr | Cutaneous leukemic infiltration following varicella - a case of
Wolf's isotopic response |
title_full_unstemmed | Cutaneous leukemic infiltration following varicella - a case of
Wolf's isotopic response |
title_short | Cutaneous leukemic infiltration following varicella - a case of
Wolf's isotopic response |
title_sort | cutaneous leukemic infiltration following varicella - a case of
wolf's isotopic response |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324999/ https://www.ncbi.nlm.nih.gov/pubmed/28300900 http://dx.doi.org/10.1590/abd1806-4841.20164686 |
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