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Clinical utility of metabolic syndrome severity scores: considerations for practitioners

The metabolic syndrome (MetS) is marked by abnormalities in central obesity, high blood pressure, high triglycerides, low high-density lipoprotein-cholesterol, and high fasting glucose and appears to be produced by underlying processes of inflammation, oxidative stress, and adipocyte dysfunction. Me...

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Autores principales: DeBoer, Mark D, Gurka, Matthew J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325095/
https://www.ncbi.nlm.nih.gov/pubmed/28255250
http://dx.doi.org/10.2147/DMSO.S101624
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author DeBoer, Mark D
Gurka, Matthew J
author_facet DeBoer, Mark D
Gurka, Matthew J
author_sort DeBoer, Mark D
collection PubMed
description The metabolic syndrome (MetS) is marked by abnormalities in central obesity, high blood pressure, high triglycerides, low high-density lipoprotein-cholesterol, and high fasting glucose and appears to be produced by underlying processes of inflammation, oxidative stress, and adipocyte dysfunction. MetS has traditionally been classified based on dichotomous criteria that deny that MetS-related risk likely exists as a spectrum. Continuous MetS scores provide a way to track MetS-related risk over time. We generated MetS severity scores that are sex- and race/ethnicity-specific, acknowledging that the way MetS is manifested may be different by sex and racial/ethnic subgroup. These scores are correlated with long-term risk for type 2 diabetes mellitus and cardiovascular disease. Clinical use of scores like these provide a potential opportunity to identify patients at highest risk, motivate patients toward lifestyle change, and follow treatment progress over time.
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spelling pubmed-53250952017-03-02 Clinical utility of metabolic syndrome severity scores: considerations for practitioners DeBoer, Mark D Gurka, Matthew J Diabetes Metab Syndr Obes Review The metabolic syndrome (MetS) is marked by abnormalities in central obesity, high blood pressure, high triglycerides, low high-density lipoprotein-cholesterol, and high fasting glucose and appears to be produced by underlying processes of inflammation, oxidative stress, and adipocyte dysfunction. MetS has traditionally been classified based on dichotomous criteria that deny that MetS-related risk likely exists as a spectrum. Continuous MetS scores provide a way to track MetS-related risk over time. We generated MetS severity scores that are sex- and race/ethnicity-specific, acknowledging that the way MetS is manifested may be different by sex and racial/ethnic subgroup. These scores are correlated with long-term risk for type 2 diabetes mellitus and cardiovascular disease. Clinical use of scores like these provide a potential opportunity to identify patients at highest risk, motivate patients toward lifestyle change, and follow treatment progress over time. Dove Medical Press 2017-02-20 /pmc/articles/PMC5325095/ /pubmed/28255250 http://dx.doi.org/10.2147/DMSO.S101624 Text en © 2017 DeBoer and Gurka. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
DeBoer, Mark D
Gurka, Matthew J
Clinical utility of metabolic syndrome severity scores: considerations for practitioners
title Clinical utility of metabolic syndrome severity scores: considerations for practitioners
title_full Clinical utility of metabolic syndrome severity scores: considerations for practitioners
title_fullStr Clinical utility of metabolic syndrome severity scores: considerations for practitioners
title_full_unstemmed Clinical utility of metabolic syndrome severity scores: considerations for practitioners
title_short Clinical utility of metabolic syndrome severity scores: considerations for practitioners
title_sort clinical utility of metabolic syndrome severity scores: considerations for practitioners
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325095/
https://www.ncbi.nlm.nih.gov/pubmed/28255250
http://dx.doi.org/10.2147/DMSO.S101624
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