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Statin therapy reduces the likelihood of suboptimal blood pressure control among Ugandan adult diabetic patients

BACKGROUND: Hypertension is one of the recognized risk factors of cardiovascular diseases in adult diabetic patients. High prevalence of suboptimal blood pressure (BP) control has been well documented in the majority of studies assessing BP control in diabetic patients in sub-Saharan Africa. In Ugan...

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Autores principales: Lumu, William, Kampiire, Leaticia, Akabwai, George Patrick, Kiggundu, Daniel Ssekikubo, Kibirige, Davis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325131/
https://www.ncbi.nlm.nih.gov/pubmed/28260908
http://dx.doi.org/10.2147/TCRM.S120423
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author Lumu, William
Kampiire, Leaticia
Akabwai, George Patrick
Kiggundu, Daniel Ssekikubo
Kibirige, Davis
author_facet Lumu, William
Kampiire, Leaticia
Akabwai, George Patrick
Kiggundu, Daniel Ssekikubo
Kibirige, Davis
author_sort Lumu, William
collection PubMed
description BACKGROUND: Hypertension is one of the recognized risk factors of cardiovascular diseases in adult diabetic patients. High prevalence of suboptimal blood pressure (BP) control has been well documented in the majority of studies assessing BP control in diabetic patients in sub-Saharan Africa. In Uganda, there is a dearth of similar studies. This study evaluated the prevalence and correlates of suboptimal BP control in an adult diabetic population in Uganda. PATIENTS AND METHODS: This was a cross-sectional study that enrolled 425 eligible ambulatory adult diabetic patients attending three urban diabetic outpatient clinics over 11 months. Data about their sociodemographic characteristics and clinical history were collected using pre-tested questionnaires. Suboptimal BP control was defined according to the 2015 American Diabetes Association standards of diabetes care guideline as BP levels ≥140/90 mmHg. RESULTS: The mean age of the study participants was 52.2±14.4 years, with the majority being females (283, 66.9%). Suboptimal BP control was documented in 192 (45.3%) study participants and was independently associated with the study site (private hospitals; odds ratio 2.01, 95% confidence interval 1.18–3.43, P=0.01) and use of statin therapy (odds ratio 0.5, 95% confidence interval 0.26–0.96, P=0.037). CONCLUSION: Suboptimal BP control was highly prevalent in this study population. Strategies to improve optimal BP control, especially in the private hospitals, and the use of statin therapy should be encouraged in adult diabetic patients.
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spelling pubmed-53251312017-03-03 Statin therapy reduces the likelihood of suboptimal blood pressure control among Ugandan adult diabetic patients Lumu, William Kampiire, Leaticia Akabwai, George Patrick Kiggundu, Daniel Ssekikubo Kibirige, Davis Ther Clin Risk Manag Original Research BACKGROUND: Hypertension is one of the recognized risk factors of cardiovascular diseases in adult diabetic patients. High prevalence of suboptimal blood pressure (BP) control has been well documented in the majority of studies assessing BP control in diabetic patients in sub-Saharan Africa. In Uganda, there is a dearth of similar studies. This study evaluated the prevalence and correlates of suboptimal BP control in an adult diabetic population in Uganda. PATIENTS AND METHODS: This was a cross-sectional study that enrolled 425 eligible ambulatory adult diabetic patients attending three urban diabetic outpatient clinics over 11 months. Data about their sociodemographic characteristics and clinical history were collected using pre-tested questionnaires. Suboptimal BP control was defined according to the 2015 American Diabetes Association standards of diabetes care guideline as BP levels ≥140/90 mmHg. RESULTS: The mean age of the study participants was 52.2±14.4 years, with the majority being females (283, 66.9%). Suboptimal BP control was documented in 192 (45.3%) study participants and was independently associated with the study site (private hospitals; odds ratio 2.01, 95% confidence interval 1.18–3.43, P=0.01) and use of statin therapy (odds ratio 0.5, 95% confidence interval 0.26–0.96, P=0.037). CONCLUSION: Suboptimal BP control was highly prevalent in this study population. Strategies to improve optimal BP control, especially in the private hospitals, and the use of statin therapy should be encouraged in adult diabetic patients. Dove Medical Press 2017-02-20 /pmc/articles/PMC5325131/ /pubmed/28260908 http://dx.doi.org/10.2147/TCRM.S120423 Text en © 2017 Lumu et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Original Research
Lumu, William
Kampiire, Leaticia
Akabwai, George Patrick
Kiggundu, Daniel Ssekikubo
Kibirige, Davis
Statin therapy reduces the likelihood of suboptimal blood pressure control among Ugandan adult diabetic patients
title Statin therapy reduces the likelihood of suboptimal blood pressure control among Ugandan adult diabetic patients
title_full Statin therapy reduces the likelihood of suboptimal blood pressure control among Ugandan adult diabetic patients
title_fullStr Statin therapy reduces the likelihood of suboptimal blood pressure control among Ugandan adult diabetic patients
title_full_unstemmed Statin therapy reduces the likelihood of suboptimal blood pressure control among Ugandan adult diabetic patients
title_short Statin therapy reduces the likelihood of suboptimal blood pressure control among Ugandan adult diabetic patients
title_sort statin therapy reduces the likelihood of suboptimal blood pressure control among ugandan adult diabetic patients
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325131/
https://www.ncbi.nlm.nih.gov/pubmed/28260908
http://dx.doi.org/10.2147/TCRM.S120423
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