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Human Alpha-1-Antitrypsin (hAAT) therapy reduces renal dysfunction and acute tubular necrosis in a murine model of bilateral kidney ischemia-reperfusion injury

Several lines of evidence have demonstrated the anti-inflammatory and cytoprotective effects of alpha-1-antitrypsin (AAT), the major serum serine protease inhibitor. The aim of the present study was to investigate the effects of human AAT (hAAT) monotherapy during the early and recovery phase of isc...

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Detalles Bibliográficos
Autores principales:	Maicas, Nuria, van der Vlag, Johan, Bublitz, Janin, Florquin, Sandrine, Bakker-van Bebber, Marinka, Dinarello, Charles A., Verweij, Vivienne, Masereeuw, Roos, Joosten, Leo A., Hilbrands, Luuk B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325207/ https://www.ncbi.nlm.nih.gov/pubmed/28235038 http://dx.doi.org/10.1371/journal.pone.0168981

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