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Phosphatidylinositide 3-kinase (PI3K) and PI3K-related kinase (PIKK) activity contributes to radioresistance in thyroid carcinomas

Anaplastic (ATC) and certain follicular thyroid-carcinomas (FTCs) are radioresistant. The Phosphatidylinositide 3-kinase (PI3K) pathway is commonly hyperactivated in thyroid-carcinomas. PI3K can modify the PI3K-related kinases (PIKKs) in response to radiation: How PIKKs interact with PI3K and contri...

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Detalles Bibliográficos
Autores principales:	Burrows, Natalie, Williams, Joseph, Telfer, Brian A, Resch, Julia, Valentine, Helen R, Fitzmaurice, Richard J, Eustace, Amanda, Irlam, Joely, Rowling, Emily J, Hoang-Vu, Cuong, West, Catharine M, Brabant, Georg, Williams, Kaye J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325350/ https://www.ncbi.nlm.nih.gov/pubmed/27527858 http://dx.doi.org/10.18632/oncotarget.11056

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