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Hypoxia enhances the malignant nature of bladder cancer cells and concomitantly antagonizes protein O-glycosylation extension

Invasive bladder tumours express the cell-surface Sialyl-Tn (STn) antigen, which stems from a premature stop in protein O-glycosylation. The STn antigen favours invasion, immune escape, and possibly chemotherapy resistance, making it attractive for target therapeutics. However, the events leading to...

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Detalles Bibliográficos
Autores principales:	Peixoto, Andreia, Fernandes, Elisabete, Gaiteiro, Cristiana, Lima, Luís, Azevedo, Rita, Soares, Janine, Cotton, Sofia, Parreira, Beatriz, Neves, Manuel, Amaro, Teresina, Tavares, Ana, Teixeira, Filipe, Palmeira, Carlos, Rangel, Maria, Silva, André M.N., Reis, Celso A., Santos, Lúcio Lara, Oliveira, Maria José, Ferreira, José Alexandre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325352/ https://www.ncbi.nlm.nih.gov/pubmed/27542232 http://dx.doi.org/10.18632/oncotarget.11257

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