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Validation of a network-based strategy for the optimization of combinatorial target selection in breast cancer therapy: siRNA knockdown of network targets in MDA-MB-231 cells as an in vitro model for inhibition of tumor development
Network-based strategies provided by systems biology are attractive tools for cancer therapy. Modulation of cancer networks by anticancer drugs may alter the response of malignant cells and/or drive network re-organization into the inhibition of cancer progression. Previously, using systems biology...
Autores principales: | Tilli, Tatiana M., Carels, Nicolas, Tuszynski, Jack A., Pasdar, Manijeh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325356/ https://www.ncbi.nlm.nih.gov/pubmed/27527857 http://dx.doi.org/10.18632/oncotarget.11055 |
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