Subclones in B-lymphoma cell lines: isogenic models for the study of gene regulation

Genetic heterogeneity though common in tumors has been rarely documented in cell lines. To examine how often B-lymphoma cell lines are comprised of subclones, we performed immunoglobulin (IG) heavy chain hypermutation analysis. Revealing that subclones are not rare in B-cell lymphoma cell lines, 6/4...

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Detalles Bibliográficos
Autores principales: Quentmeier, Hilmar, Pommerenke, Claudia, Ammerpohl, Ole, Geffers, Robert, Hauer, Vivien, MacLeod, Roderick AF, Nagel, Stefan, Romani, Julia, Rosati, Emanuela, Rosén, Anders, Uphoff, Cord C, Zaborski, Margarete, Drexler, Hans G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325377/
https://www.ncbi.nlm.nih.gov/pubmed/27566572
http://dx.doi.org/10.18632/oncotarget.11524

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