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Protein arginine methyltransferase 1 is a novel regulator of MYCN in neuroblastoma

Amplification or overexpression of MYCN is associated with poor prognosis of human neuroblastoma. We have recently defined a MYCN-dependent transcriptional signature, including protein arginine methyltransferase 1 (PRMT1), which identifies a subgroup of patients with high-risk disease. Here we provi...

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Detalles Bibliográficos
Autores principales: Eberhardt, Allison, Hansen, Jeanne N., Koster, Jan, Lotta, Louis T., Wang, Simeng, Livingstone, Emmett, Qian, Kun, Valentijn, Linda J., Zheng, Yujun George, Schor, Nina F., Li, Xingguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325390/
https://www.ncbi.nlm.nih.gov/pubmed/27571165
http://dx.doi.org/10.18632/oncotarget.11556