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NOD2 up-regulates TLR2-mediated IL-23p19 expression via NF-κB subunit c-Rel in Paneth cell-like cells

IL-23p19 plays important roles in intestinal antimicrobial immunity, while its over-expression can lead to intestinal inflammation. However, the bacterial compounds and the type of pattern recognition receptor involved in the inducible expression of IL-23p19 in Paneth cells remain unclear. Here we s...

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Detalles Bibliográficos
Autores principales: Tan, Gao, Liang, Erbo, Liao, Kaili, Deng, Feihong, Zhang, Wendi, Chen, Yuqing, Xu, Jun, Zhi, Fachao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325392/
https://www.ncbi.nlm.nih.gov/pubmed/27563808
http://dx.doi.org/10.18632/oncotarget.11467