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NOD2 up-regulates TLR2-mediated IL-23p19 expression via NF-κB subunit c-Rel in Paneth cell-like cells
IL-23p19 plays important roles in intestinal antimicrobial immunity, while its over-expression can lead to intestinal inflammation. However, the bacterial compounds and the type of pattern recognition receptor involved in the inducible expression of IL-23p19 in Paneth cells remain unclear. Here we s...
Autores principales: | Tan, Gao, Liang, Erbo, Liao, Kaili, Deng, Feihong, Zhang, Wendi, Chen, Yuqing, Xu, Jun, Zhi, Fachao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325392/ https://www.ncbi.nlm.nih.gov/pubmed/27563808 http://dx.doi.org/10.18632/oncotarget.11467 |
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