Defective CFTR- β-catenin interaction promotes NF-κB nuclear translocation and intestinal inflammation in cystic fibrosis

While inflammation with aberrant activation of NF-κB pathway is a hallmark of cystic fibrosis (CF), the molecular mechanisms underlying the link between CFTR defect and activation of NF-κB-mediated pro-inflammatory response remain elusive. Here, we investigated the link between CFTR defect and NF-κB...

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Detalles Bibliográficos
Autores principales: Liu, Kaisheng, Zhang, Xiaohu, Zhang, Jie Ting, Tsang, Lai Ling, Jiang, Xiaohua, Chan, Hsiao Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325423/
https://www.ncbi.nlm.nih.gov/pubmed/27588407
http://dx.doi.org/10.18632/oncotarget.11747

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