Dual role of the integrated stress response in medulloblastoma tumorigenesis

In response to endoplasmic reticulum (ER) stress, activation of pancreatic ER kinase (PERK) coordinates an adaptive program known as the integrated stress response (ISR) by phosphorylating translation initiation factor 2α (eIF2α). Phosphorylated eIF2α is quickly dephosphorylated by the protein phosp...

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Detalles Bibliográficos
Autores principales: Stone, Sarrabeth, Ho, Yeung, Li, Xiting, Jamison, Stephanie, Harding, Heather P., Ron, David, Lin, Wensheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325430/
https://www.ncbi.nlm.nih.gov/pubmed/27802424
http://dx.doi.org/10.18632/oncotarget.11873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325430/
https://www.ncbi.nlm.nih.gov/pubmed/27802424
http://dx.doi.org/10.18632/oncotarget.11873

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