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Dual role of the integrated stress response in medulloblastoma tumorigenesis
In response to endoplasmic reticulum (ER) stress, activation of pancreatic ER kinase (PERK) coordinates an adaptive program known as the integrated stress response (ISR) by phosphorylating translation initiation factor 2α (eIF2α). Phosphorylated eIF2α is quickly dephosphorylated by the protein phosp...
Autores principales: | Stone, Sarrabeth, Ho, Yeung, Li, Xiting, Jamison, Stephanie, Harding, Heather P., Ron, David, Lin, Wensheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325430/ https://www.ncbi.nlm.nih.gov/pubmed/27802424 http://dx.doi.org/10.18632/oncotarget.11873 |
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