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Regulation of matrix metalloproteinases (MMPs) expression and secretion in MDA-MB-231 breast cancer cells by LIM and SH3 protein 1 (LASP1)

The process of tumor invasion requires degradation of extracellular matrix by proteolytic enzymes. Cancer cells form protrusive invadopodia, which produce and release matrix metalloproteinases (MMPs) to degrade the basement membrane thereby enabling metastasis. We investigated the effect of LASP1, a...

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Detalles Bibliográficos
Autores principales:	Endres, Marcel, Kneitz, Susanne, Orth, Martin F., Perera, Ruwan K., Zernecke, Alma, Butt, Elke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325439/ https://www.ncbi.nlm.nih.gov/pubmed/27588391 http://dx.doi.org/10.18632/oncotarget.11720

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