Activation of the A2B adenosine receptor in B16 melanomas induces CXCL12 expression in FAP-positive tumor stromal cells, enhancing tumor progression

The A2B receptor (A2BR) can mediate adenosine-induced tumor proliferation, immunosuppression and angiogenesis. Targeting the A2BR has proved to be therapeutically effective in some murine tumor models, but the mechanisms of these effects are still incompletely understood. Here, we report that pharma...

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Detalles Bibliográficos
Autores principales: Sorrentino, Claudia, Miele, Lucio, Porta, Amalia, Pinto, Aldo, Morello, Silvana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325441/
https://www.ncbi.nlm.nih.gov/pubmed/27590504
http://dx.doi.org/10.18632/oncotarget.11729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325441/
https://www.ncbi.nlm.nih.gov/pubmed/27590504
http://dx.doi.org/10.18632/oncotarget.11729

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