Characterizing the immune microenvironment of malignant peripheral nerve sheath tumor by PD-L1 expression and presence of CD8+ tumor infiltrating lymphocytes

BACKGROUND: Malignant peripheral nerve sheath tumor (MPNST) is an aggressive sarcoma with few treatment options. Tumor immune state has not been characterized in MPNST, and is important in determining response to immune checkpoint blockade. Our aim was to evaluate the expression of programmed death-...

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Detalles Bibliográficos
Autores principales: Shurell, Elizabeth, Singh, Arun S., Crompton, Joseph G., Jensen, Sarah, Li, Yunfeng, Dry, Sarah, Nelson, Scott, Chmielowski, Bartosz, Bernthal, Nicholas, Federman, Noah, Tumeh, Paul, Eilber, Fritz C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325443/
https://www.ncbi.nlm.nih.gov/pubmed/27588404
http://dx.doi.org/10.18632/oncotarget.11734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325443/
https://www.ncbi.nlm.nih.gov/pubmed/27588404
http://dx.doi.org/10.18632/oncotarget.11734

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