The iron chelator deferasirox induces apoptosis by targeting oncogenic Pyk2/β-catenin signaling in human multiple myeloma

Deregulated iron metabolism underlies the pathogenesis of many human cancers. Recently, low expression of ferroportin, which is the only identified non-heme iron exporter, has been associated with significantly reduced overall survival in multiple myeloma (MM); however, the altered iron metabolism i...

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Detalles Bibliográficos
Autores principales: Kamihara, Yusuke, Takada, Kohichi, Sato, Tsutomu, Kawano, Yutaka, Murase, Kazuyuki, Arihara, Yohei, Kikuchi, Shohei, Hayasaka, Naotaka, Usami, Makoto, Iyama, Satoshi, Miyanishi, Koji, Sato, Yasushi, Kobune, Masayoshi, Kato, Junji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325446/
https://www.ncbi.nlm.nih.gov/pubmed/27602957
http://dx.doi.org/10.18632/oncotarget.11830

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325446/
https://www.ncbi.nlm.nih.gov/pubmed/27602957
http://dx.doi.org/10.18632/oncotarget.11830

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