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Differential contribution of APP metabolites to early cognitive deficits in a TgCRND8 mouse model of Alzheimer’s disease

Alzheimer’s disease (AD) is a neurodegenerative pathology commonly characterized by a progressive and irreversible deterioration of cognitive functions, especially memory. Although the etiology of AD remains unknown, a consensus has emerged on the amyloid hypothesis, which posits that increased prod...

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Detalles Bibliográficos
Autores principales:	Hamm, Valentine, Héraud, Céline, Bott, Jean-Bastien, Herbeaux, Karine, Strittmatter, Carole, Mathis, Chantal, Goutagny, Romain
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325539/ https://www.ncbi.nlm.nih.gov/pubmed/28275722 http://dx.doi.org/10.1126/sciadv.1601068

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