NFATc1 phosphorylation by DYRK1A increases its protein stability

NFATs are transcription factors involved in immune activation and tumor progression. Previous reports showed that DYRK1A suppressed NFATc2 transcriptional activity through phosphorylation. Nonetheless, our results showed that DYRK1A increased NFATc1/αA protein level and subsequent transcriptional ac...

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Detalles Bibliográficos
Autores principales: Liu, Heng, Wang, Ketao, Chen, Shuai, Sun, Qian, Zhang, Yuankai, Chen, Long, Sun, Xiulian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325557/
https://www.ncbi.nlm.nih.gov/pubmed/28235034
http://dx.doi.org/10.1371/journal.pone.0172985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325557/
https://www.ncbi.nlm.nih.gov/pubmed/28235034
http://dx.doi.org/10.1371/journal.pone.0172985

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