Picornavirus RNA is protected from cleavage by ribonuclease during virion uncoating and transfer across cellular and model membranes

Picornaviruses are non-enveloped RNA viruses that enter cells via receptor-mediated endocytosis. Because they lack an envelope, picornaviruses face the challenge of delivering their RNA genomes across the membrane of the endocytic vesicle into the cytoplasm to initiate infection. Currently, the mech...

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Detalles Bibliográficos
Autores principales: Groppelli, Elisabetta, Levy, Hazel C., Sun, Eileen, Strauss, Mike, Nicol, Clare, Gold, Sarah, Zhuang, Xiaowei, Tuthill, Tobias J., Hogle, James M., Rowlands, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325612/
https://www.ncbi.nlm.nih.gov/pubmed/28166307
http://dx.doi.org/10.1371/journal.ppat.1006197

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