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Analysis of a cAMP regulated coactivator family reveals an alternative phosphorylation motif for AMPK family members

The second messenger cAMP stimulates cellular gene expression via the PKA-mediated phosphorylation of the transcription factor CREB and through dephosphorylation of the cAMP-responsive transcriptional coactivators (CRTCs). Under basal conditions, CRTCs are phosphorylated by members of the AMPK famil...

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Detalles Bibliográficos
Autores principales:	Sonntag, Tim, Moresco, James J., Vaughan, Joan M., Matsumura, Shigenobu, Yates, John R., Montminy, Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325614/ https://www.ncbi.nlm.nih.gov/pubmed/28235073 http://dx.doi.org/10.1371/journal.pone.0173013

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