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Hippocampal activation is associated with longitudinal amyloid accumulation and cognitive decline

The amyloid hypothesis suggests that beta-amyloid (Aβ) deposition leads to alterations in neural function and ultimately to cognitive decline in Alzheimer’s disease. However, factors that underlie Aβ deposition are incompletely understood. One proposed model suggests that synaptic activity leads to...

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Detalles Bibliográficos
Autores principales:	Leal, Stephanie L, Landau, Susan M, Bell, Rachel K, Jagust, William J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5325620/ https://www.ncbi.nlm.nih.gov/pubmed/28177283 http://dx.doi.org/10.7554/eLife.22978

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