Cargando…
Séroprévalence des marqueurs viraux sur les dons du sang au Centre de Transfusion Sanguine, Hôpital Militaire d’Instruction Mohammed V de Rabat
This study aims to determine the prevalence of human immunodeficiency virus (HIV) infections and hepatitis B virus (HBV) and hepatitis C virus (HCV) infections among blood donors at the Blood Donor Center, Mohammed V Military Teaching Hospital between 2010 and 2012. We conducted a retrospective stud...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The African Field Epidemiology Network
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326047/ https://www.ncbi.nlm.nih.gov/pubmed/28292147 http://dx.doi.org/10.11604/pamj.2016.25.185.6266 |
_version_ | 1782510478979760128 |
---|---|
author | Uwingabiye, Jean Zahid, Hafidi Unyendje, Loubet Hadef, Rachid |
author_facet | Uwingabiye, Jean Zahid, Hafidi Unyendje, Loubet Hadef, Rachid |
author_sort | Uwingabiye, Jean |
collection | PubMed |
description | This study aims to determine the prevalence of human immunodeficiency virus (HIV) infections and hepatitis B virus (HBV) and hepatitis C virus (HCV) infections among blood donors at the Blood Donor Center, Mohammed V Military Teaching Hospital between 2010 and 2012. We conducted a retrospective study among military blood donors aged 18-50 years, with a male predominance (95%). Pre-donation interview is the first selection barrier for individuals at risk. Biological screening was performed by liquid enzyme immunoassay technique using antibodies and/or antigen. Fourth generation combined HCV and HIV antigen/antibody ELISA (enzyme-linked immunosorbent assay) test was used. The Blood Donor Center and the laboratory of virology used the same technique performed in duplicate to confirm results. Out of 25661 tested samples, the prevalence rate of HBV infections was 3.97 ‰ (n = 102), the prevalence rate of HCV infections was 2.45 ‰ (n = 63) and the prevalence rate of HIV infections was 0.15 ‰ (n = 4). A single case with HBV and HCV virus co-infection (0.039 ‰) was registered, no association between HIV-HBV, HIV-HCV or HBV, HCV and HIV infections was recorded. The low seroprevalence rates of viral markers recorded in our study show improvement in preventive measures for donor selection and screening tests. The registered prevalence encourages the use of combined reagent, which is the only alternative to molecular biology in developing countries. |
format | Online Article Text |
id | pubmed-5326047 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | The African Field Epidemiology Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-53260472017-03-10 Séroprévalence des marqueurs viraux sur les dons du sang au Centre de Transfusion Sanguine, Hôpital Militaire d’Instruction Mohammed V de Rabat Uwingabiye, Jean Zahid, Hafidi Unyendje, Loubet Hadef, Rachid Pan Afr Med J Case Series This study aims to determine the prevalence of human immunodeficiency virus (HIV) infections and hepatitis B virus (HBV) and hepatitis C virus (HCV) infections among blood donors at the Blood Donor Center, Mohammed V Military Teaching Hospital between 2010 and 2012. We conducted a retrospective study among military blood donors aged 18-50 years, with a male predominance (95%). Pre-donation interview is the first selection barrier for individuals at risk. Biological screening was performed by liquid enzyme immunoassay technique using antibodies and/or antigen. Fourth generation combined HCV and HIV antigen/antibody ELISA (enzyme-linked immunosorbent assay) test was used. The Blood Donor Center and the laboratory of virology used the same technique performed in duplicate to confirm results. Out of 25661 tested samples, the prevalence rate of HBV infections was 3.97 ‰ (n = 102), the prevalence rate of HCV infections was 2.45 ‰ (n = 63) and the prevalence rate of HIV infections was 0.15 ‰ (n = 4). A single case with HBV and HCV virus co-infection (0.039 ‰) was registered, no association between HIV-HBV, HIV-HCV or HBV, HCV and HIV infections was recorded. The low seroprevalence rates of viral markers recorded in our study show improvement in preventive measures for donor selection and screening tests. The registered prevalence encourages the use of combined reagent, which is the only alternative to molecular biology in developing countries. The African Field Epidemiology Network 2016-11-24 /pmc/articles/PMC5326047/ /pubmed/28292147 http://dx.doi.org/10.11604/pamj.2016.25.185.6266 Text en © Jean Uwingabiye et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Series Uwingabiye, Jean Zahid, Hafidi Unyendje, Loubet Hadef, Rachid Séroprévalence des marqueurs viraux sur les dons du sang au Centre de Transfusion Sanguine, Hôpital Militaire d’Instruction Mohammed V de Rabat |
title | Séroprévalence des marqueurs viraux sur les dons du sang au Centre de Transfusion Sanguine, Hôpital Militaire d’Instruction Mohammed V de Rabat |
title_full | Séroprévalence des marqueurs viraux sur les dons du sang au Centre de Transfusion Sanguine, Hôpital Militaire d’Instruction Mohammed V de Rabat |
title_fullStr | Séroprévalence des marqueurs viraux sur les dons du sang au Centre de Transfusion Sanguine, Hôpital Militaire d’Instruction Mohammed V de Rabat |
title_full_unstemmed | Séroprévalence des marqueurs viraux sur les dons du sang au Centre de Transfusion Sanguine, Hôpital Militaire d’Instruction Mohammed V de Rabat |
title_short | Séroprévalence des marqueurs viraux sur les dons du sang au Centre de Transfusion Sanguine, Hôpital Militaire d’Instruction Mohammed V de Rabat |
title_sort | séroprévalence des marqueurs viraux sur les dons du sang au centre de transfusion sanguine, hôpital militaire d’instruction mohammed v de rabat |
topic | Case Series |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326047/ https://www.ncbi.nlm.nih.gov/pubmed/28292147 http://dx.doi.org/10.11604/pamj.2016.25.185.6266 |
work_keys_str_mv | AT uwingabiyejean seroprevalencedesmarqueursvirauxsurlesdonsdusangaucentredetransfusionsanguinehopitalmilitairedinstructionmohammedvderabat AT zahidhafidi seroprevalencedesmarqueursvirauxsurlesdonsdusangaucentredetransfusionsanguinehopitalmilitairedinstructionmohammedvderabat AT unyendjeloubet seroprevalencedesmarqueursvirauxsurlesdonsdusangaucentredetransfusionsanguinehopitalmilitairedinstructionmohammedvderabat AT hadefrachid seroprevalencedesmarqueursvirauxsurlesdonsdusangaucentredetransfusionsanguinehopitalmilitairedinstructionmohammedvderabat |