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Survie au cancer du sein à Rabat (Maroc) 2005-2008

INTRODUCTION: Breast cancer is a public health problem in Morocco. This study aims to estimate the survival rate for patients with breast cancer living in Rabat. METHODS: We conducted a prognostic study of female patients with breast cancer diagnosed during 2005-2008, living in Rabat and whose data...

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Autores principales: Mechita, Nada Bennani, Tazi, Mohammed Adnane, Er-Raki, Abdelouahed, Mrabet, Mustapha, Saadi, Asma, Benjaafar, Noureddine, Razine, Rachid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326062/
https://www.ncbi.nlm.nih.gov/pubmed/28292106
http://dx.doi.org/10.11604/pamj.2016.25.144.10402
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author Mechita, Nada Bennani
Tazi, Mohammed Adnane
Er-Raki, Abdelouahed
Mrabet, Mustapha
Saadi, Asma
Benjaafar, Noureddine
Razine, Rachid
author_facet Mechita, Nada Bennani
Tazi, Mohammed Adnane
Er-Raki, Abdelouahed
Mrabet, Mustapha
Saadi, Asma
Benjaafar, Noureddine
Razine, Rachid
author_sort Mechita, Nada Bennani
collection PubMed
description INTRODUCTION: Breast cancer is a public health problem in Morocco. This study aims to estimate the survival rate for patients with breast cancer living in Rabat. METHODS: We conducted a prognostic study of female patients with breast cancer diagnosed during 2005-2008, living in Rabat and whose data were recorded in the Rabat Cancer Registry. The date of inclusion in this study corresponded with the date on which cancer was histologically confirmed. Survival rate was estimated using the Kaplan-Meier method and the comparison between the different classes of a variable was made using the log rank test. The study of factors associated with survival was performed using the Cox model. RESULTS: During the study period 628 cases of breast cancer were collected. Mortality rate was 19.9%. Overall 1-year survival rate was 97.1%, 89.2% at 3 years and 80.6% at 5 years. In multivariate analysis, breast cancer survival was statistically lower in patients over 70 years of age (p <0.001) with large tumor size (p < 0.001), advanced-stage adenopathies (p = 0.007), metastases (p < 0.001) and not using hormone therapy (p = 0.002). CONCLUSION: Large tumor size and metastases are poor prognostic factors in breast cancer, hence the need to strengthen screening programs.
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spelling pubmed-53260622017-03-10 Survie au cancer du sein à Rabat (Maroc) 2005-2008 Mechita, Nada Bennani Tazi, Mohammed Adnane Er-Raki, Abdelouahed Mrabet, Mustapha Saadi, Asma Benjaafar, Noureddine Razine, Rachid Pan Afr Med J Research INTRODUCTION: Breast cancer is a public health problem in Morocco. This study aims to estimate the survival rate for patients with breast cancer living in Rabat. METHODS: We conducted a prognostic study of female patients with breast cancer diagnosed during 2005-2008, living in Rabat and whose data were recorded in the Rabat Cancer Registry. The date of inclusion in this study corresponded with the date on which cancer was histologically confirmed. Survival rate was estimated using the Kaplan-Meier method and the comparison between the different classes of a variable was made using the log rank test. The study of factors associated with survival was performed using the Cox model. RESULTS: During the study period 628 cases of breast cancer were collected. Mortality rate was 19.9%. Overall 1-year survival rate was 97.1%, 89.2% at 3 years and 80.6% at 5 years. In multivariate analysis, breast cancer survival was statistically lower in patients over 70 years of age (p <0.001) with large tumor size (p < 0.001), advanced-stage adenopathies (p = 0.007), metastases (p < 0.001) and not using hormone therapy (p = 0.002). CONCLUSION: Large tumor size and metastases are poor prognostic factors in breast cancer, hence the need to strengthen screening programs. The African Field Epidemiology Network 2016-11-11 /pmc/articles/PMC5326062/ /pubmed/28292106 http://dx.doi.org/10.11604/pamj.2016.25.144.10402 Text en © Nada Bennani Mechita et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Mechita, Nada Bennani
Tazi, Mohammed Adnane
Er-Raki, Abdelouahed
Mrabet, Mustapha
Saadi, Asma
Benjaafar, Noureddine
Razine, Rachid
Survie au cancer du sein à Rabat (Maroc) 2005-2008
title Survie au cancer du sein à Rabat (Maroc) 2005-2008
title_full Survie au cancer du sein à Rabat (Maroc) 2005-2008
title_fullStr Survie au cancer du sein à Rabat (Maroc) 2005-2008
title_full_unstemmed Survie au cancer du sein à Rabat (Maroc) 2005-2008
title_short Survie au cancer du sein à Rabat (Maroc) 2005-2008
title_sort survie au cancer du sein à rabat (maroc) 2005-2008
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326062/
https://www.ncbi.nlm.nih.gov/pubmed/28292106
http://dx.doi.org/10.11604/pamj.2016.25.144.10402
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