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Survie au cancer du sein à Rabat (Maroc) 2005-2008
INTRODUCTION: Breast cancer is a public health problem in Morocco. This study aims to estimate the survival rate for patients with breast cancer living in Rabat. METHODS: We conducted a prognostic study of female patients with breast cancer diagnosed during 2005-2008, living in Rabat and whose data...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The African Field Epidemiology Network
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326062/ https://www.ncbi.nlm.nih.gov/pubmed/28292106 http://dx.doi.org/10.11604/pamj.2016.25.144.10402 |
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author | Mechita, Nada Bennani Tazi, Mohammed Adnane Er-Raki, Abdelouahed Mrabet, Mustapha Saadi, Asma Benjaafar, Noureddine Razine, Rachid |
author_facet | Mechita, Nada Bennani Tazi, Mohammed Adnane Er-Raki, Abdelouahed Mrabet, Mustapha Saadi, Asma Benjaafar, Noureddine Razine, Rachid |
author_sort | Mechita, Nada Bennani |
collection | PubMed |
description | INTRODUCTION: Breast cancer is a public health problem in Morocco. This study aims to estimate the survival rate for patients with breast cancer living in Rabat. METHODS: We conducted a prognostic study of female patients with breast cancer diagnosed during 2005-2008, living in Rabat and whose data were recorded in the Rabat Cancer Registry. The date of inclusion in this study corresponded with the date on which cancer was histologically confirmed. Survival rate was estimated using the Kaplan-Meier method and the comparison between the different classes of a variable was made using the log rank test. The study of factors associated with survival was performed using the Cox model. RESULTS: During the study period 628 cases of breast cancer were collected. Mortality rate was 19.9%. Overall 1-year survival rate was 97.1%, 89.2% at 3 years and 80.6% at 5 years. In multivariate analysis, breast cancer survival was statistically lower in patients over 70 years of age (p <0.001) with large tumor size (p < 0.001), advanced-stage adenopathies (p = 0.007), metastases (p < 0.001) and not using hormone therapy (p = 0.002). CONCLUSION: Large tumor size and metastases are poor prognostic factors in breast cancer, hence the need to strengthen screening programs. |
format | Online Article Text |
id | pubmed-5326062 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | The African Field Epidemiology Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-53260622017-03-10 Survie au cancer du sein à Rabat (Maroc) 2005-2008 Mechita, Nada Bennani Tazi, Mohammed Adnane Er-Raki, Abdelouahed Mrabet, Mustapha Saadi, Asma Benjaafar, Noureddine Razine, Rachid Pan Afr Med J Research INTRODUCTION: Breast cancer is a public health problem in Morocco. This study aims to estimate the survival rate for patients with breast cancer living in Rabat. METHODS: We conducted a prognostic study of female patients with breast cancer diagnosed during 2005-2008, living in Rabat and whose data were recorded in the Rabat Cancer Registry. The date of inclusion in this study corresponded with the date on which cancer was histologically confirmed. Survival rate was estimated using the Kaplan-Meier method and the comparison between the different classes of a variable was made using the log rank test. The study of factors associated with survival was performed using the Cox model. RESULTS: During the study period 628 cases of breast cancer were collected. Mortality rate was 19.9%. Overall 1-year survival rate was 97.1%, 89.2% at 3 years and 80.6% at 5 years. In multivariate analysis, breast cancer survival was statistically lower in patients over 70 years of age (p <0.001) with large tumor size (p < 0.001), advanced-stage adenopathies (p = 0.007), metastases (p < 0.001) and not using hormone therapy (p = 0.002). CONCLUSION: Large tumor size and metastases are poor prognostic factors in breast cancer, hence the need to strengthen screening programs. The African Field Epidemiology Network 2016-11-11 /pmc/articles/PMC5326062/ /pubmed/28292106 http://dx.doi.org/10.11604/pamj.2016.25.144.10402 Text en © Nada Bennani Mechita et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Mechita, Nada Bennani Tazi, Mohammed Adnane Er-Raki, Abdelouahed Mrabet, Mustapha Saadi, Asma Benjaafar, Noureddine Razine, Rachid Survie au cancer du sein à Rabat (Maroc) 2005-2008 |
title | Survie au cancer du sein à Rabat (Maroc) 2005-2008 |
title_full | Survie au cancer du sein à Rabat (Maroc) 2005-2008 |
title_fullStr | Survie au cancer du sein à Rabat (Maroc) 2005-2008 |
title_full_unstemmed | Survie au cancer du sein à Rabat (Maroc) 2005-2008 |
title_short | Survie au cancer du sein à Rabat (Maroc) 2005-2008 |
title_sort | survie au cancer du sein à rabat (maroc) 2005-2008 |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326062/ https://www.ncbi.nlm.nih.gov/pubmed/28292106 http://dx.doi.org/10.11604/pamj.2016.25.144.10402 |
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