Long-term treatment of clarithromycin at a low concentration improves hydrogen peroxide-induced oxidant/antioxidant imbalance in human small airway epithelial cells by increasing Nrf2 mRNA expression

BACKGROUND: Clarithromycin (CAM), a representative macrolide antibiotic, has been used widely at low doses for long-term therapy of chronic inflammatory airway diseases. Anti-inflammatory effects of macrolide antibiotics were first discovered in clinical practice. Although oxidative stress is known...

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Detalles Bibliográficos
Autores principales: Iwayama, Kuninori, Kusakabe, Ayuko, Ohtsu, Keisuke, Nawano, Takahiro, Tatsunami, Ryosuke, Ohtaki, Ko-ichi, Tampo, Yoshiko, Hayase, Nobumasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326501/
https://www.ncbi.nlm.nih.gov/pubmed/28235416
http://dx.doi.org/10.1186/s40360-017-0119-8

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