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BaalChIP: Bayesian analysis of allele-specific transcription factor binding in cancer genomes

Allele-specific measurements of transcription factor binding from ChIP-seq data are key to dissecting the allelic effects of non-coding variants and their contribution to phenotypic diversity. However, most methods of detecting an allelic imbalance assume diploid genomes. This assumption severely li...

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Detalles Bibliográficos
Autores principales:	de Santiago, Ines, Liu, Wei, Yuan, Ke, O’Reilly, Martin, Chilamakuri, Chandra Sekhar Reddy, Ponder, Bruce A. J., Meyer, Kerstin B., Markowetz, Florian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326502/ https://www.ncbi.nlm.nih.gov/pubmed/28235418 http://dx.doi.org/10.1186/s13059-017-1165-7

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