Evolution from genetics to phenotype: reinterpretation of NSCLC plasticity, heterogeneity, and drug resistance

Lung cancer is the leading cause of cancer-related deaths worldwide. Targeted therapy is beneficial in most cases, but the development of drug resistance stands as an obstacle to good prognosis. Multiple mechanisms were explored such as genetic alterations, activation of bypass signaling, and phenot...

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Detalles Bibliográficos
Autores principales: Xue, Yingjiao, Hou, Shenda, Ji, Hongbin, Han, Xiangkun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326619/
https://www.ncbi.nlm.nih.gov/pubmed/27757846
http://dx.doi.org/10.1007/s13238-016-0330-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326619/
https://www.ncbi.nlm.nih.gov/pubmed/27757846
http://dx.doi.org/10.1007/s13238-016-0330-1

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