Mitochondrial DNA Activates the NLRP3 Inflammasome and Predisposes to Type 1 Diabetes in Murine Model

Although a correlation between polymorphisms of NOD-like receptor family-pyrin domain containing 3 (NLRP3) and predisposition to type 1 diabetes (T1D) has been identified, the potential function and activation of the NLRP3 inflammasome in T1D have not been clarified. The present study shows that non...

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Detalles Bibliográficos
Autores principales: Carlos, Daniela, Costa, Frederico R. C., Pereira, Camila A., Rocha, Fernanda A., Yaochite, Juliana N. U., Oliveira, Gabriela G., Carneiro, Fernando S., Tostes, Rita C., Ramos, Simone G., Zamboni, Dario S., Camara, Niels O. S., Ryffel, Bernhard, Silva, João S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326761/
https://www.ncbi.nlm.nih.gov/pubmed/28289409
http://dx.doi.org/10.3389/fimmu.2017.00164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326761/
https://www.ncbi.nlm.nih.gov/pubmed/28289409
http://dx.doi.org/10.3389/fimmu.2017.00164

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