Cargando…
Discovery of Compounds that Positively Modulate the High Affinity Choline Transporter
Cholinergic hypofunction is associated with decreased attention and cognitive deficits in the central nervous system in addition to compromised motor function. Consequently, stimulation of cholinergic neurotransmission is a rational therapeutic approach for the potential treatment of a variety of ne...
Autores principales: | Choudhary, Parul, Armstrong, Emma J., Jorgensen, Csilla C., Piotrowski, Mary, Barthmes, Maria, Torella, Rubben, Johnston, Sarah E., Maruyama, Yuya, Janiszewski, John S., Storer, R. Ian, Skerratt, Sarah E., Benn, Caroline L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326799/ https://www.ncbi.nlm.nih.gov/pubmed/28289374 http://dx.doi.org/10.3389/fnmol.2017.00040 |
Ejemplares similares
-
Insulin Regulates the Activity of the High-Affinity Choline Transporter CHT
por: Fishwick, Katherine J., et al.
Publicado: (2015) -
Discovery of High-Affinity Protein Binding Ligands – Backwards
por: Diehnelt, Chris W., et al.
Publicado: (2010) -
Upregulation of the high-affinity choline transporter in colon relieves stress-induced hyperalgesia
por: Lin, Meng-Juan, et al.
Publicado: (2018) -
Self-assembling choline mimicks with enhanced binding affinities to C-LytA protein
por: Shi, Yang, et al.
Publicado: (2014) -
Blockage of High-Affinity Choline Transporter Increases Visceral Hypersensitivity in Rats with Chronic Stress
por: Zhao, Chen, et al.
Publicado: (2018)