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Toll‐like receptor 4 signalling mediates inflammation in skeletal muscle of patients with chronic kidney disease

BACKGROUND: Inflammation in skeletal muscle is implicated in the pathogenesis of insulin resistance and cachexia but why uremia up‐regulates pro‐inflammatory cytokines is unknown. Toll‐like receptors (TLRs) regulate locally the innate immune responses, but it is unknown whether in chronic kidney dis...

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Detalles Bibliográficos
Autores principales: Verzola, Daniela, Bonanni, Alice, Sofia, Antonella, Montecucco, Fabrizio, D'Amato, Elena, Cademartori, Valeria, Parodi, Emanuele Luigi, Viazzi, Francesca, Venturelli, Chiara, Brunori, Giuliano, Garibotto, Giacomo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5326826/
https://www.ncbi.nlm.nih.gov/pubmed/27897392
http://dx.doi.org/10.1002/jcsm.12129